Article
Genotypic and phenotypic diversity of Mycobacterium tuberculosis complex genotypes prevalent in West Africa.
PloS one - 1 Jan 2021
Osei-Wusu Stephen, Otchere Isaac Darko, Morgan Portia, Musah Abdul Basit, Siam Ishaque Mintah, Asandem Diana, Afum Theophilus, Asare Prince, Asante-Poku Adwoa, Kusi Kwadwo Asamoah, Gagneux Sebastien, Yeboah-Manu Dorothy
Abstract excerpt
Findings from previous comparative genomics studies of the Mycobacterium tuberculosis complex (MTBC) suggest genomic variation among the genotypes may have phenotypic implications. We investigated the diversity in the phenotypic profiles of the main prevalent MTBC genotypes in West Africa. Thirty-six whole genome sequenced drug susceptible MTBC isolates belonging to lineages 4, 5 and 6 were included in this...
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