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Comparative genomics and epidemic success of Mycobacterium tuberculosis lineage 4 in eastern China.

BMC genomics - 6 Jun 2026

Zhou Zong-Lei, Wu Qi, Liu Zheng-Wei, Wang Wei-Bing

Abstract excerpt

BACKGROUND: Mycobacterium tuberculosis (Mtb) lineage 4 (L4) remains as a crucial component of the pathogen. Genetic factors potentiate the spread of Mtb, while the genomic feature and epidemic success at individual level of L4 strains have not been fully illustrated, especially in China. Therefore, the current study aimed to obtain additional understanding on the pan-genome architecture and transmission of the...

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Identifiers

PMID: 42249289
DOI: 10.1186/s12864-026-13035-9
PMCID: PMC13465446

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