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Article

Pharmacogenetics for genes associated with age-related macular degeneration in the Comparison of AMD Treatments Trials (CATT).

Ophthalmology - 1 Mar 2013

Hagstrom Stephanie A, Ying Gui-Shuang, Pauer Gayle J T, Sturgill-Short Gwen M, Huang Jiayan, Callanan David G, Kim Ivana K, Klein Michael L, Maguire Maureen G, Martin Daniel F

Abstract excerpt

PURPOSE: To evaluate the pharmacogenetic relationship between genotypes of single nucleotide polymorphisms (SNPs) known to be associated with age-related macular degeneration (AMD) and response to treatment with ranibizumab (Lucentis; Genentech, South San Francisco, CA) or bevacizumab (Avastin; Genentech) for neovascular AMD. DESIGN: Clinical trial. PARTICIPANTS: Eight hundred thirty-four (73%) of 1149 patients...

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Source

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Identifiers

PMID: 23337555
DOI: 10.1016/j.ophtha.2012.11.037
PMCID: PMC3633658

Genes

ARMS2
CFH
HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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