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Article

Genetic influences on the outcome of anti-vascular endothelial growth factor treatment in neovascular age-related macular degeneration.

Ophthalmology - 1 Aug 2013

Abedi Farshad, Wickremasinghe Sanjeewa, Richardson Andrea J, Islam Amirul F M, Guymer Robyn H, Baird Paul N

Abstract excerpt

PURPOSE: To determine the association of genetic variants in known age-related macular degeneration (AMD) risk-associated genes with outcome of anti-vascular endothelial growth factor (VEGF) treatment in neovascular AMD. DESIGN: Prospective cohort study. PARTICIPANTS: We enrolled 224 consecutive patients with neovascular AMD at the Royal Victorian Eye and Ear Hospital, Australia. METHODS: Patients were treated...

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Source

Identifiers

PMID: 23582991
DOI: 10.1016/j.ophtha.2013.01.014

Genes

ARMS2
HTRA1
CFB
CFH
CFHR1

Variants

rs800292
rs10490924

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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