Article
T Follicular Helper Cells in Transplantation.
Transplantation - 1 Aug 2016
Walters Giles Desmond, Vinuesa Carola G
Abstract excerpt
The recently described T follicular helper (Tfh) cell is required for the production of high affinity antibody. After contact with follicular dendritic cells, Tfh cells move into the germinal centre and provide help to B cells both by direct B cell-T cell interaction and production of IL-21. This drives proliferation, differentiation, and affinity maturation of the B cells to produce plasma cells capable of...
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