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Forward Genetics in Toxoplasma gondii Reveals a Family of Rhoptry Kinases That Mediates Pathogenesis

23 May 2009

Abstract excerpt

Toxoplasma gondii is a widespread protozoan parasite that commonly infects domestic, wild, and companion animals (8). Like related tissue coccidians, T. gondii has a complex life cycle alternating between a sexual cycle, which occurs only within enterocytes of the small intestines of cats (all members of the Felidae appear to be susceptible), and asexual propagation in a variety of warm-blooded vertebrate hosts...

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PMID: 19465561
DOI: 10.1128/ec.00107-09

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