Article
Splicing factor hSlu7 contains a unique functional domain required to retain the protein within the nucleus.
Molecular biology of the cell - 1 Aug 2004
Shomron Noam, Reznik Mika, Ast Gil
Abstract excerpt
Precursor-mRNA splicing removes the introns and ligates the exons to form a mature mRNA. This process is carried out in a spliceosomal complex containing >150 proteins and five small nuclear ribonucleoproteins. Splicing protein hSlu7 is required for correct selection of the 3' splice site. Here, we identify by bioinformatics and mutational analyses three functional domains of the hSlu7 protein that have distinct...
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