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Article

Integrated microRNA, gene expression and transcription factors signature in papillary thyroid cancer with lymph node metastasis

15 Jun 2016

Abstract excerpt

Background. Papillary thyroid carcinoma (PTC) is the commonest thyroid malignancy originating from the follicle cells in the thyroid. Despite a good overall prognosis, certain high-risk cases as in those with lymph node metastasis (LNM) have progressive disease and poorer prognosis. MicroRNAs are a class of non-protein-coding, 19-24 nucleotides single-stranded RNAs which regulate gene expression and these...

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PMID: 27350898
DOI: 10.7717/peerj.2119

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