Article
Identification of Specific Long Non-Coding RNA Expression: Profile and Analysis of Association with Clinicopathologic Characteristics and BRAF Mutation in Papillary Thyroid Cancer.
Thyroid : official journal of the American Thyroid Association - 1 Dec 2016
Wang Qiangfeng, Yang Huanxia, Wu Lingjiao, Yao Jian, Meng Xiaohua, Jiang Han, Xiao Cheng, Wu Fusheng
Abstract excerpt
BACKGROUND: In recent years, long non-coding RNAs (lncRNAs) have been shown to play a critical regulatory role in cancer biology. However, the contribution of lncRNAs to papillary thyroid cancer (PTC) remains largely unknown. METHODS: RNA sequencing and quantitative reverse transcription polymerase chain reaction were used to detect and verify changes to the transcriptome profile in 12 PTC tissues compared to...
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