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Integrated Proteomics and Transcriptomics Identify a FN1-ANXA1-PTK2B Network Driving Lymph Node Metastasis in Papillary Thyroid Carcinoma

2026-06-16

Abstract excerpt

<title>Abstract</title> <p>Purpose Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy. While most patients have a favorable prognosis, lymph node metastasis (LNM) occurs in a significant proportion of cases, leading to treatment failure. Elucidating the molecular mechanisms of PTC metastasis is crucial for identifying new therapeutic targets. Methods Transcriptomic data from TCGA were use...

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Literature Corpus work
7bb6ef46-d795-5270-9e22-8e57996e070d
DOI
10.21203/rs.3.rs-9688961/v1
Open publication

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Integrated Proteomics and Transcriptomics Identify a FN1-ANXA1-PTK2B Network Driving Lymph Node Metastasis in Papillary Thyroid CarcinomaDOI 10.21203/rs.3.rs-9688961/v1
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