Article
BRAF mutation, selected miRNAs and genes expression in primary papillary thyroid carcinomas and local lymph node metastases.
Pathology, research and practice - 1 Jun 2024
Kalfert David, Ludvikova Marie, Pesta Martin, Hakala Tommi, Dostalova Lucie, Grundmannova Hana, Windrichova Jindra, Houfkova Katerina, Knizkova Tereza, Ludvik Jaroslav, Polivka Jiri, Kholova Ivana
Abstract excerpt
Mutations in cancer-related genes are now known to be accompanied by epigenetic events in carcinogenesis by modification of the regulatory pathways and expression of genes involved in the pathobiology. Such cancer-related mutations, miRNAs and gene expression may be promising molecular markers of the most common papillary thyroid carcinoma (PTC). However, there are limited data on their relationships. The aim of...
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