Article
Mutant allele of rna14 in fission yeast affects pre-mRNA splicing.
Journal of genetics - 1 Jun 2016
Yadav Sudhanshu, Sonkar Amit, Ahamad Nafees, Ahmed Shakil
Abstract excerpt
Spliceosome and 3'-end processing complexes are necessary for the precursor mRNA (pre-mRNA) maturation. Spliceosome complex removes noncoding introns, while 3'-end processing involves in cleavage and addition of poly(A) tails to the nascent transcript. Rna14 protein in budding yeast has been implicated in cleavage and polyadenylation of mRNA in the nucleus but their role in the pre-mRNA splicing has not been...
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