Article
Identification of the Rare, Four Repeat Allele of IL-4 Intron-3 VNTR Polymorphism in Indian Populations.
Iranian journal of immunology : IJI - 1 Jun 2016
Verma Henu Kumar, Jha Aditya Nath, Khodiar Prafulla Kumar, Patra Pradeep Kumar, Bhaskar Lakkakula Venkata Kameswara Subrahmanya
Abstract excerpt
BACKGROUND: Cytokines are cell signaling molecules which upon release by cells facilitate the recruitment of immune-modulatory cells towards the sites of inflammation. Genetic variations in cytokine genes are shown to regulate their production and affect the risk of infectious as well as autoimmune diseases. Intron-3 of interleukin-4 gene (IL-4) harbors 70-bp variable number of tandem repeats (VNTR) that may...
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