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Article

Inflammatory gene variants in the Tsimane, an indigenous Bolivian population with a high infectious load.

Biodemography and social biology - 1 Jan 2011

Vasunilashorn Sarinnapha, Finch Caleb E, Crimmins Eileen M, Vikman Suvi A, Stieglitz Jonathan, Gurven Michael, Kaplan Hillard, Allayee Hooman

Abstract excerpt

The Tsimane of lowland Bolivia are an indigenous forager-farmer population living under conditions resembling pre-industrial European populations, with high infectious morbidity, high infection and inflammation, and shortened life expectancy. Analysis of 917 persons ages 5 to 60+ showed that allele frequencies of 9 SNPs examined in the apolipoprotein E (apoE), C-reactive protein (CRP), and interleukin-6 (IL-6)...

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PMID: 21845926
DOI: 10.1080/19485565.2011.564475
PMCID: PMC3529658

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