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Article

Analysis of genetic variants in the IL4 promoter and VNTR loci in Indian patients with Visceral Leishmaniasis.

Human immunology - 1 Dec 2014

Mishra Anshuman, Jha Aditya Nath, van Tong Hoang, Singh Vipin Kumar, Gomes Carlos E M, Singh Lalji, Velavan Thirumalaisamy P, Thangaraj Kumarasamy

Abstract excerpt

Visceral Leishmaniasis (VL) is the most severest form of Leishmaniasis and resistance to infection is mediated by cellular immune responses. Interleukin 4 (IL-4) orchestrates of Th2 and Th1 immune responses during infections. In this study, we aimed to investigate possible association between three functional IL-4 polymorphisms -590C/T (rs2243250), -34C/T (rs2070874) and 70bp VNTR (rs79071878 in intron3) with VL...

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PMID: 25454624
DOI: 10.1016/j.humimm.2014.10.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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