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Recent Applications of In Silico Approaches for Studying Receptor Mutations Associated with Human Pathologies.

Molecules (Basel, Switzerland) - 13 Nov 2024

Pappalardo Matteo, Sipala Federica Maria, Nicolosi Milena Cristina, Guccione Salvatore, Ronsisvalle Simone

Abstract excerpt

In recent years, the advent of computational techniques to predict the potential activity of a drug interacting with a receptor or to predict the structure of unidentified proteins with aberrant characteristics has significantly impacted the field of drug design. We provide a comprehensive review of the current state of in silico approaches and software for investigating the effects of receptor mutations...

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PMID: 39598735
DOI: 10.3390/molecules29225349
PMCID: PMC11596970

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