NQO1 rs1800566 polymorph is more prone to NOx induced lung injury: Endorsing deleterious functionality through informatics approach.

doi:10.1016/j.gene.2016.06.048

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Article

NQO1 rs1800566 polymorph is more prone to NOx induced lung injury: Endorsing deleterious functionality through informatics approach.

Gene - 10 Oct 2016

Basharat Zarrin, Messaoudi Abdelmonaem, Ruba Sehrish, Yasmin Azra

Abstract excerpt

Gene-environment interaction studies have led to the identification of genetic mutations in individuals with increased susceptibility to pollution related diseases. rs1800566 polymorphism of NQO1, leading to P187S missense mutation in the transcribed antioxidant protein, causes individuals carrying this mutation more prone to NO2 induced lung inflammatory injury. Here, we report significant structural and...

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Identifiers

PMID: 27349566
DOI: 10.1016/j.gene.2016.06.048

Genes

NQO1

Variants

rs1800566

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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