Article
Killer cell immunoglobulin-like receptor and human leukocyte antigen gene profiles in a cohort of HIV-infected Mexican Mestizos.
Immunogenetics - 1 Oct 2016
Garrido-Rodríguez Daniela, Ávila-Ríos Santiago, García-Morales Claudia, Valenzuela-Ponce Humberto, Ormsby Christopher, Reyes-Gopar Helena, Fernandez-Lopez Juan Carlos, Reyes-Terán Gustavo
Abstract excerpt
Killer cell immunoglobulin-like receptors (KIRs) represent the most polymorphic genes responsible for natural killer cell function, while human leukocyte antigen (HLA) class I molecules define and restrict cytotoxic T lymphocyte responses. Specific KIR, HLA, or KIR-HLA combinations have been implicated in the outcome of human immunodeficiency virus (HIV) disease. The remarkable polymorphism of KIR and HLA genes...
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