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Duplication and divergence of the retrovirus restriction gene <i>Fv1</i> in <i>Mus caroli</i> mice allows protection from multiple retroviruses

2019-10-11

Abstract excerpt

Viruses and their hosts are locked in an evolutionary race where resistance to infection is acquired by the hosts while viruses develop strategies to circumvent these host defenses. Forming one arm of the host defense armory are cell autonomous restriction factors like Fv1. Originally described as protecting laboratory mice from infection by murine leukemia virus (MLV), Fv1s from some wild mice have also been foun...

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Literature Corpus work
f2c1acf6-06d0-5d61-8794-cca6228cd9e6
DOI
10.1101/802363
Open publication

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Duplication and divergence of the retrovirus restriction gene <i>Fv1</i> in <i>Mus caroli</i> mice allows protection from multiple retrovirusesDOI 10.1101/802363
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