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Article

MDA-9/Syntenin (SDCBP) modulates small GTPases RhoA and Cdc42 via transforming growth factor β1 to enhance epithelial-mesenchymal transition in breast cancer.

Oncotarget - 6 Dec 2016

Menezes Mitchell E, Shen Xue-Ning, Das Swadesh K, Emdad Luni, Sarkar Devanand, Fisher Paul B

Abstract excerpt

Epithelial-mesenchymal transition (EMT) is one of the decisive steps regulating cancer invasion and metastasis. However, the molecular mechanisms underlying this transition require further clarification. MDA-9/syntenin (SDCBP) expression is elevated in breast cancer patient samples as well as cultured breast cancer cells. Silencing expression of MDA-9 in mesenchymal metastatic breast cancer cells triggered a...

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Identifiers

PMID: 27863394
DOI: 10.18632/oncotarget.13373
PMCID: PMC5348312

Genes

SDCBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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