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Article

Digastric Muscle Phenotypes of the Ts65Dn Mouse Model of Down Syndrome.

PloS one - 1 Jan 2016

Glass Tiffany J, Connor Nadine P

Abstract excerpt

Down syndrome is frequently associated with complex difficulties in oromotor development, feeding, and swallowing. However, the muscle phenotypes underlying these deficits are unclear. We tested the hypotheses that the Ts65Dn mouse model of DS has significantly altered myosin heavy chain (MyHC) isoform profiles of the muscles involved in feeding and swallowing, as well as reductions in the speed of these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27336944
DOI: 10.1371/journal.pone.0158008
PMCID: PMC4919106

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SDS

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