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Article

Paradoxical Hypersusceptibility of Drug-resistant Mycobacteriumtuberculosis to β-lactam Antibiotics.

EBioMedicine - 1 Jul 2016

Cohen Keira A, El-Hay Tal, Wyres Kelly L, Weissbrod Omer, Munsamy Vanisha, Yanover Chen, Aharonov Ranit, Shaham Oded, Conway Thomas C, Goldschmidt Yaara, Bishai William R, Pym Alexander S

Abstract excerpt

Mycobacterium tuberculosis (M. tuberculosis) is considered innately resistant to β-lactam antibiotics. However, there is evidence that susceptibility to β-lactam antibiotics in combination with β-lactamase inhibitors is variable among clinical isolates, and these may present therapeutic options for drug-resistant cases. Here we report our investigation of susceptibility to β-lactam/β-lactamase inhibitor...

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Identifiers

PMID: 27333036
DOI: 10.1016/j.ebiom.2016.05.041
PMCID: PMC4972527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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