Article
Escherichia coli Chromosomal Loci Segregate from Midcell with Universal Dynamics.
Biophysical journal - 21 Jun 2016
Cass Julie A, Kuwada Nathan J, Traxler Beth, Wiggins Paul A
Abstract excerpt
The structure of the Escherichia coli chromosome is inherently dynamic over the duration of the cell cycle. Genetic loci undergo both stochastic motion around their initial positions and directed motion to opposite poles of the rod-shaped cell during segregation. We developed a quantitative method to characterize cell-cycle dynamics of the E. coli chromosome to probe the chromosomal steady-state mobility and...
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