Article
Cooperative effect of the VP1 amino acids 98E, 145A and 169F in the productive infection of mouse cell lines by enterovirus 71 (BS strain).
Emerging microbes & infections - 22 Jun 2016
Victorio Carla Bianca Luena, Xu Yishi, Ng Qimei, Meng Tao, Chow Vincent Tk, Chua Kaw Bing
Abstract excerpt
Enterovirus 71 (EV71) is a neurotrophic virus that causes hand, foot and mouth disease (HFMD) and occasional neurological infection among children. It infects primate cells but not rodent cells, primarily due to the incompatibility between the virus and the expressed form of its receptor, scavenger receptor class B member 2 (SCARB2) protein, on rodent cells (mSCARB2). We previously generated adapted strains...
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