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Article

Identification of site-specific adaptations conferring increased neural cell tropism during human enterovirus 71 infection.

PLoS pathogens - 1 Jan 2012

Cordey Samuel, Petty Tom J, Schibler Manuel, Martinez Yannick, Gerlach Daniel, van Belle Sandra, Turin Lara, Zdobnov Evgeny, Kaiser Laurent, Tapparel Caroline

Abstract excerpt

Enterovirus 71 (EV71) is one of the most virulent enteroviruses, but the specific molecular features that enhance its ability to disseminate in humans remain unknown. We analyzed the genomic features of EV71 in an immunocompromised host with disseminated disease according to the different sites of infection. Comparison of five full-length genomes sequenced directly from respiratory, gastrointestinal, nervous...

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Identifiers

PMID: 22910880
DOI: 10.1371/journal.ppat.1002826
PMCID: PMC3406088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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