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Article

Multiple-level validation identifies PARK2 in the development of lung cancer and chronic obstructive pulmonary disease.

Oncotarget - 12 Jul 2016

Lee SeungBaek, She Jun, Deng Bo, Kim JungJin, de Andrade Mariza, Na Jie, Sun Zhifu, Wampfler Jason A, Cunningham Julie M, Wu Yanhong, Limper Andrew H, Aubry Marie-Christine, Wendt Chris, Biterman Peter, Yang Ping, Lou Zhenkun

Abstract excerpt

An important precursor to lung cancer development is chronic obstructive pulmonary disease (COPD), independent of exposure to tobacco smoke. Both diseases are associated with increased host susceptibility, inflammation, and genomic instability. However, validation of the candidate genes and functional confirmation to test shared genetic contribution and cellular mechanisms to the development of lung cancer in...

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Identifiers

PMID: 27329585
DOI: 10.18632/oncotarget.9954
PMCID: PMC5190090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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