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Article

Impaired lymphatic function accelerates cancer growth.

Oncotarget - 19 Jul 2016

Steinskog Eli Sihn Samdal, Sagstad Solfrid Johanne, Wagner Marek, Karlsen Tine Veronica, Yang Ning, Markhus Carl Erik, Yndestad Synnøve, Wiig Helge, Eikesdal Hans Petter

Abstract excerpt

Increased lymphangiogenesis is a common feature of cancer development and progression, yet the influence of impaired lymphangiogenesis on tumor growth is elusive. C3HBA breast cancer and KHT-1 sarcoma cell lines were implanted orthotopically in Chy mice, harboring a heterozygous inactivating mutation of vascular endothelial growth factor receptor-3, resulting in impaired dermal lymphangiogenesis. Accelerated...

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Identifiers

PMID: 27329584
DOI: 10.18632/oncotarget.9953
PMCID: PMC5216761

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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