Article
Molecular characterization of a Han Chinese family with essential hypertension.
Genetics and molecular research : GMR - 13 May 2016
Zhu J F, Zhang X, Ling L
Abstract excerpt
Mutations in the mitochondrial genome have been found to be associated with essential hypertension. Here, we report the clinical and molecular characterization of a three-generation Han Chinese family with maternally inherited hypertension. Most strikingly, this pedigree exhibited a high penetrance of hypertension. Sequence analysis of the mitochondrial genome showed the presence of a homoplasmic T16189C mutation...
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