Article
Systematic analysis of the clinical and biochemical characteristics of maternally inherited hypertension in Chinese Han families associated with mitochondrial.
BMC medical genomics - 24 Dec 2014
Liu Yuqi, Zhu Qinglei, Zhu Chao, Wang Xueping, Yang Jie, Yin Tong, Gao Jinliao, Li Zongbin, Ma Qinghua, Guan Minxin, Li Yang, Chen Yundai
Abstract excerpt
BACKGROUND: Mitochondrial DNA mutations may be associated with cardiovascular disease, including the common cardiac vascular disease, hypertension. METHODS: In this study we performed segregation analysis and systematically evaluated the entire mitochondrial genome in nine maternally inherited hypertension probands from Chinese Han families. We also performed clinical, genetic and molecular characterization of 74...
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