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Clinical and molecular characterization of a Han Chinese family with high penetrance of essential hypertension.

Mitochondrial DNA - 1 Dec 2012

Teng Lili, Zheng Jing, Leng Jianhang, Ding Yu

Abstract excerpt

Mutations in mitochondrial DNA are associated with cardiovascular diseases. We reported here molecular characterization of a three-generation Han Chinese family with maternally transmitted hypertension. Most strikingly, this family exhibited a high penetrance of hypertension. Sequence analysis of mitochondrial genome showed the presence of 12,338T>C mutation and 12,330A>G mutation and distinct sets of...

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Source

Identifiers

PMID: 22917175
DOI: 10.3109/19401736.2012.710205

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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