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Article

Direct-acting Antiviral Agents Resistance-associated Polymorphisms in Chinese Treatment-naïve Patients Infected with Genotype 1b Hepatitis C Virus.

Chinese medical journal - 5 Oct 2015

Wang Ye, Rao Hui-Ying, Xie Xing-Wang, Wei Lai

Abstract excerpt

BACKGROUND: It has been reported that several baseline polymorphisms of direct-acting antivirals (DAAs) agents resistance-associated variants (RAVs) would affect the treatment outcomes of patients chronically infected with hepatitis C virus (CHC). The aim of this study is to investigate the prevalence of DAAs RAVs in treatment-naÏve GT1b CHC patients. METHODS: Direct sequencing and ultra-deep sequencing of the...

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Identifiers

PMID: 26415801
DOI: 10.4103/0366-6999.166038
PMCID: PMC4736847

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