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Article

The incidence of resistance-associated variants to NS5A in HCV subtypes 1a and 1b in Taiwan.

Biomedical journal - 1 Dec 2021

Tsai Ming-Chao, Hung Chao-Hung, Lu Sheng-Nan, Wang Jing-Houng, Chen Chien-Hung, Kee Kwong-Ming, Chang Kuo-Chin, Chao Tsai-Ling, Hu Tsung-Hui

Abstract excerpt

BACKGROUND: Resistance-associated variants (RAVs) to direct-antiviral agents (DAAs) may hamper treatment. There was a lack of data on the natural prevalence of RAVs in Taiwanese HCV-infected patients. We investigated the real-life presence of RAVs in the nonstructural 5A (NS5A) region in HCV genotype 1a and 1b in chronically infected individuals in Taiwan. METHODS: In this single-center cohort study, nested...

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Source

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Identifiers

PMID: 35123932
DOI: 10.1016/j.bj.2020.08.004
PMCID: PMC9038949

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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