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Article

Association of 3q13.32 variants with hip trochanter and intertrochanter bone mineral density identified by a genome-wide association study.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Nov 2016

Pei Y-F, Xie Z-G, Wang X-Y, Hu W-Z, Li L-B, Ran S, Lin Y, Hai R, Shen H, Tian Q, Zhang Y-H, Lei S-F, Papasian C J, Deng H-W, Zhang L

Abstract excerpt

We performed a GWAS of trochanter and intertrochanter bone mineral density (BMD) in the Framingham Heart Study and replicated in three independent studies. Our results identified one novel locus around the associated variations at chromosomal region 3q13.32 and replicated two loci at chromosomal regions 3p21 and 8q24. Our findings provide useful insights that enhance our understanding of bone development,...

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Identifiers

PMID: 27311723
DOI: 10.1007/s00198-016-3663-y

Genes

TRO
CTNNB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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