Article
Reversion of β-Cell Autoimmunity Changes Risk of Type 1 Diabetes: TEDDY Study.
Diabetes care - 1 Sept 2016
Vehik Kendra, Lynch Kristian F, Schatz Desmond A, Akolkar Beena, Hagopian William, Rewers Marian, She Jin-Xiong, Simell Olli, Toppari Jorma, Ziegler Anette-G, Lernmark Åke, Bonifacio Ezio, Krischer Jeffrey P
Abstract excerpt
OBJECTIVE: β-Cell autoantibodies are a feature of the preclinical phase of type 1 diabetes. Here, we asked how frequently they revert in a cohort of children at risk for type 1 diabetes and whether reversion has any effect on type 1 diabetes risk. RESEARCH DESIGN AND METHODS: Children were up to 10 years of age and screened more than once for insulin autoantibody, GAD antibody, and insulinoma antigen-2...
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