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Article

Precision Targeted Mutagenesis via Cas9 Paired Nickases in Rice.

Plant & cell physiology - 1 May 2016

Mikami Masafumi, Toki Seiichi, Endo Masaki

Abstract excerpt

Recent reports of CRISPR- (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR-associated protein 9) mediated heritable mutagenesis in plants highlight the need for accuracy of the mutagenesis directed by this system. Off-target mutations are an important issue when considering functional gene analysis, as well as the molecular breeding of crop plants with large genome size, i.e. with many...

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Identifiers

PMID: 26936792
DOI: 10.1093/pcp/pcw049
PMCID: PMC4867050

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Source receipt: pubmed, retrieved 7 Sept 2026.

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