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Article

MicroRNA-mRNA interactions underlying colorectal cancer molecular subtypes.

Nature communications - 17 Nov 2015

Cantini Laura, Isella Claudio, Petti Consalvo, Picco Gabriele, Chiola Simone, Ficarra Elisa, Caselle Michele, Medico Enzo

Abstract excerpt

Colorectal cancer (CRC) transcriptional subtypes have been recently identified by gene expression profiling. Here we describe an analytical pipeline, microRNA master regulator analysis (MMRA), developed to search for microRNAs potentially driving CRC subtypes. Starting from a microRNA-mRNA tumour expression data set, MMRA identifies candidate regulator microRNAs by assessing their subtype-specific expression,...

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Identifiers

PMID: 27305450
DOI: 10.1038/ncomms9878
PMCID: PMC4660217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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