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Long noncoding RNA profiles identify five distinct molecular subtypes of colorectal cancer with clinical relevance

2 Jun 2014

Abstract excerpt

Colorectal cancer (CRC) is a heterogeneous disease in terms of clinical behavior and response to therapy. Increasing evidence suggests that long noncoding RNAs (lncRNAs) are frequently aberrantly expressed in cancers, and some of them have been implicated in CRC biogenesis and prognosis. Using an lncRNA-mining approach, we constructed lncRNAs expression profiles in approximately 888 CRC samples. By applying...

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PMID: 24954858
DOI: 10.1016/j.molonc.2014.05.010

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