Article
A multidimensional network approach reveals microRNAs as determinants of the mesenchymal colorectal cancer subtype.
Oncogene - 17 Nov 2016
Fessler E, Jansen M, De Sousa E Melo F, Zhao L, Prasetyanti P R, Rodermond H, Kandimalla R, Linnekamp J F, Franitza M, van Hooff S R, de Jong J H, Oppeneer S C, van Noesel C J M, Dekker E, Stassi G, Wang X, Medema J P, Vermeulen L
Abstract excerpt
Colorectal cancer (CRC) is a heterogeneous disease posing a challenge for accurate classification and treatment of this malignancy. There is no common genetic molecular feature that would allow for the identification of patients at risk for developing recurrences and thus selecting patients who would benefit from more stringent therapies still poses a major clinical challenge. Recently, an international...
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