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Article

Association of Polymorphisms in MACRO Domain Containing 2 With Thyroid-Associated Orbitopathy.

Investigative ophthalmology & visual science - 1 Jun 2016

Khong Jwu Jin, Burdon Kathryn P, Lu Yi, Leonardos Lefta, Laurie Kate J, Walsh John P, Gajdatsy Adam D, Ebeling Peter R, McNab Alan A, Hardy Thomas G, Stawell Richard J, Davis Garry J, Selva Dinesh, Tsirbas Angelo, Montgomery Grant W, Macgregor Stuart, Craig Jamie E

Abstract excerpt

PURPOSE: Thyroid-associated orbitopathy (TO) is an autoimmune-mediated orbital inflammation that can lead to disfigurement and blindness. Multiple genetic loci have been associated with Graves' disease, but the genetic basis for TO is largely unknown. This study aimed to identify loci associated with TO in individuals with Graves' disease, using a genome-wide association scan (GWAS) for the first time to our...

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Source

Identifiers

PMID: 27304844
DOI: 10.1167/iovs.15-18797

Genes

MACROD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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