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Article

The association of thyroid peroxidase antibody risk loci with susceptibility to and phenotype of Graves' disease.

Clinical endocrinology - 1 Oct 2015

Kuś Aleksander, Szymański Konrad, Peeters Robin P, Miśkiewicz Piotr, Porcu Eleonora, Pistis Giorgio, Sanna Serena, Naitza Silvia, Płoski Rafał, Medici Marco, Bednarczuk Tomasz

Abstract excerpt

BACKGROUND: Despite great progress, the genetic basis of Graves' disease (GD) remains poorly understood. Recently, a population-based genomewide association study (GWAS) identified five novel loci (ATXN2/SH2B3, MAGI3, BACH2, TPO and KALRN) as significantly associated with the presence of thyroid peroxidase autoantibodies (TPOAbs), whereas several other loci showed suggestive association. METHODS: In this study,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25345847
DOI: 10.1111/cen.12640

Genes

MAGI3
ATXN2
TPO
BACH2
KALRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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