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Article

Pleiotropic effects of Chr15q25 nicotinic gene cluster and the relationship between smoking, cognition and ADHD.

Journal of psychiatric research - 1 Sept 2016

Schuch Jaqueline B, Polina Evelise R, Rovaris Diego L, Kappel Djenifer B, Mota Nina R, Cupertino Renata B, Silva Katiane L, Guimarães-da-Silva Paula O, Karam Rafael G, Salgado Carlos A I, White Melanie J, Rohde Luis A, Grevet Eugenio H, Bau Claiton H D

Abstract excerpt

Polymorphisms in the CHRNA5-CHRNA3-CHRNB4 gene cluster (Chr15q25) have been robustly associated with nicotine dependence, including genome-wide studies, as well as with cognitive and neuropsychological measures. In addition, cognitive processes can be influenced by nicotine use through nicotinic acetylcholine receptors (nAChRs). Here, we evaluated the effect of polymorphisms in CHRNA5-CHRNA3-CHRNB4 gene cluster...

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Share to Attention Deficit Disorder with Hyperactivity
Share to Chromosomes, Human, Pair 15

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27302872
DOI: 10.1016/j.jpsychires.2016.06.002

Genes

CHRNA5
CHRNA3
CHRNB4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Pleiotropic effects of Chr15q25 nicotinic gene cluster and the relationship between smoking, cognition and ADHD.PMID 27302872Read ↗

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