Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Virus-like particles derived from Pichia pastoris-expressed dengue virus type 1 glycoprotein elicit homotypic virus-neutralizing envelope domain III-directed antibodies

14 Jun 2016

Abstract excerpt

BACKGROUND: Four antigenically distinct serotypes (1-4) of dengue viruses (DENVs) cause dengue disease. Antibodies to any one DENV serotype have the potential to predispose an individual to more severe disease upon infection with a different DENV serotype. A dengue vaccine must elicit homotypic neutralizing antibodies to all four DENV serotypes to avoid the risk of such antibody-dependent enhancement in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophages and microbial interactions
Share to Mosquito-borne diseases and control
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27301568
DOI: 10.1186/s12896-016-0280-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Virus-like particles derived from Pichia pastoris-expressed dengue virus type 1 glycoprotein elicit homotypic virus-neutralizing envelope domain III-directed antibodiesPMID 27301568Read ↗

Pichia pastoris-Expressed Bivalent Virus-Like Particulate Vaccine Induces Domain III-Focused Bivalent Neutralizing Antibodies without Antibody-Dependent Enhancement in VivoSemantic proximity Read ↗

Expression of the dengue virus structural proteins in Pichia pastoris leads to the generation of virus-like particles.Semantic proximity Read ↗

Dengue serotype-1 virus like particles induce antibody responses following HeLa cell expressionSemantic proximity Read ↗

An Envelope-Modified Tetravalent Dengue Virus-Like-Particle Vaccine Has Implications for Flavivirus Vaccine DesignSemantic proximity Read ↗

Stabilized dengue virus 2 envelope subunit vaccine redirects the neutralizing antibody response to all E-domainsSemantic proximity Read ↗

Advances and challenges in enveloped virus-like particle (VLP)-based vaccinesSemantic proximity Read ↗

Stabilized dengue virus 2 envelope subunit vaccine redirects the neutralizing antibody response to all E-domainsSemantic proximity Read ↗

Enterovirus D68 virus-like particles expressed in Pichia pastoris potently induce neutralizing antibody responses and confer protection against lethal viral infection in miceSemantic proximity Read ↗

Plant‐made dengue virus‐like particles produced by co‐expression of structural and non‐structural proteins induce a humoral immune response in miceSemantic proximity Read ↗

An epitope-resurfaced virus-like particle can induce broad neutralizing antibody against four serotypes of dengue virusSemantic proximity Read ↗

Mammalian expression of virus-like particles as a proof of principle for next generation polio vaccinesSemantic proximity Read ↗

A Tetravalent Dengue Virus-like Particle Vaccine Induces High levels of Neutralizing Antibodies and Inhibits Dengue Replication in Non-Human PrimatesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.