Article

Dengue serotype-1 virus like particles induce antibody responses following HeLa cell expression

2026-04-10

Abstract excerpt

Dengue disease remains a significant global health threat, with current vaccines exhibiting variable efficacy and safety concerns. Virus-like particles (VLPs) offer a promising alternative by mimicking native virus structures without infectious genomes. We engineered a mammalian expression plasmid encoding Dengue-1 prM and E proteins, optimized for secretion using Japanese Encephalitis virus signal sequences, and...

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Literature Corpus work: 5fdd10c7-ac56-5340-a5ff-a1f8981c8ddd
DOI: 10.64898/2026.04.08.717190

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