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A Tetravalent Dengue Virus-like Particle Vaccine Induces High levels of Neutralizing Antibodies and Inhibits Dengue Replication in Non-Human Primates

2023-10-16

Abstract excerpt

Dengue virus (DENV) represents a significant global health burden, with 50% of the world’s population at risk of infection, and there is an urgent need for next-generation vaccines. Virus-like particle (VLP)-based vaccines, which mimic the antigenic structure of the authentic virus but lack the viral genome, are an attractive approach. Here we describe a dengue VLP (DENVLP) vaccine which generates a robust and lon...

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Identifiers and source

Literature Corpus work
a5139fc3-4930-5d02-9062-ea1c6f756144
DOI
10.1101/2023.10.16.562563
Open publication

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A Tetravalent Dengue Virus-like Particle Vaccine Induces High levels of Neutralizing Antibodies and Inhibits Dengue Replication in Non-Human PrimatesDOI 10.1101/2023.10.16.562563
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