Article
Plasmodium falciparum parasite population structure and gene flow associated to anti-malarial drugs resistance in Cambodia.
Malaria journal - 14 Jun 2016
Dwivedi Ankit, Khim Nimol, Reynes Christelle, Ravel Patrice, Ma Laurence, Tichit Magali, Bourchier Christiane, Kim Saorin, Dourng Dany, Khean Chanra, Chim Pheaktra, Siv Sovannaroth, Frutos Roger, Lek Dysoley, Mercereau-Puijalon Odile, Ariey Frédéric, Menard Didier, Cornillot Emmanuel
Abstract excerpt
BACKGROUND: Western Cambodia is recognized as the epicentre of emergence of Plasmodium falciparum multi-drug resistance. The emergence of artemisinin resistance has been observed in this area since 2008-2009 and molecular signatures associated to artemisinin resistance have been characterized in k13 gene. At present, one of the major threats faced, is the possible spread of Asian artemisinin resistant parasites...
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