Article
A barcode of multilocus nuclear DNA identifies genetic relatedness in pre- and post-Artemether/Lumefantrine treated Plasmodium falciparum in Nigeria.
BMC infectious diseases - 13 Aug 2018
Oyebola Kolapo Muyiwa, Aina Oluwagbemiga Olanrewaju, Idowu Emmanuel Taiwo, Olukosi Yetunde Adeola, Ajibaye Olusola Sunday, Otubanjo Olubunmi Adetoro, Awolola Taiwo Samson, Awandare Gordon Akanzuwine, Amambua-Ngwa Alfred
Abstract excerpt
BACKGROUND: The decline in the efficacy of artemisinin-based combination treatment (ACT) in some endemic regions threatens the progress towards global elimination of malaria. Molecular surveillance of drug resistance in malaria-endemic regions is vital to detect the emergence and spread of mutant strains. METHODS: We observed 89 malaria patients for the efficacy of artemether-lumefantrine for the treatment of...
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