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Article

Alternative splicing of DENND1A, a PCOS candidate gene, generates variant 2.

Molecular and cellular endocrinology - 15 Oct 2016

Tee Meng Kian, Speek Mart, Legeza Balázs, Modi Bhavi, Teves Maria Eugenia, McAllister Janette M, Strauss Jerome F, Miller Walter L

Abstract excerpt

Polycystic ovary syndrome (PCOS) is a common endocrinopathy characterized by hyperandrogenism and metabolic disorders. The excess androgens may be of both ovarian and adrenal origin. PCOS has a strong genetic component, and genome-wide association studies have identified several candidate genes, notably DENND1A, which encodes connecdenn 1, involved in trafficking of endosomes. DENND1A encodes two principal...

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Identifiers

PMID: 27297658
DOI: 10.1016/j.mce.2016.06.011
PMCID: PMC4983473

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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