Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alternative splicing of the androgen receptor in polycystic ovary syndrome

30 Mar 2015

Abstract excerpt

Polycystic ovary syndrome (PCOS) is one of the most common female endocrine disorders and a leading cause of female subfertility. The mechanism underlying the pathophysiology of PCOS remains to be illustrated. Here, we identify two alternative splice variants (ASVs) of the androgen receptor (AR), insertion and deletion isoforms, in granulosa cells (GCs) in ∼62% of patients with PCOS. AR ASVs are strongly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Ovarian function and disorders
Share to Sexual Differentiation and Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25825716
DOI: 10.1073/pnas.1418216112

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alternative splicing of the androgen receptor in polycystic ovary syndromePMID 25825716Read ↗

Beyond Prostate Cancer: An Androgen Receptor Splice Variant Expression in Multiple Malignancies, Non-Cancer Pathologies, and DevelopmentSemantic proximity Read ↗

Alternatively spliced androgen receptor variantsSemantic proximity Read ↗

A novel androgen receptor gene splice site mutation induces aberrant mRNA splicing and internal in-frame deletion in androgen insensitivity syndrome.Semantic proximity Read ↗

Long Noncoding RNA HUPCOS Promotes Follicular Fluid Androgen Excess in PCOS Patients via Aromatase InhibitionSemantic proximity Read ↗

Clinical significance and biological roles of lncRNA CTBP1-AS in Polycystic Ovary SyndromeSemantic proximity Read ↗

Androgen receptor signalling transactivator lncRNAs PRNCR1 and PCGEM contribute to PCOS pathogenesisSemantic proximity Read ↗

Role of Androgen Receptor for Reconsidering the “True” Polycystic Ovarian Morphology in PCOSSemantic proximity Read ↗

Delayed endometrial decidualisation in polycystic ovary syndrome; the role of AR-MAGEA11Semantic proximity Read ↗

Androgen excess: a hallmark of polycystic ovary syndrome.Semantic proximity Read ↗

Current concepts of polycystic ovary syndrome pathogenesisSemantic proximity Read ↗

Genetic Variants Associated with Hyperandrogenemia in PCOS PathophysiologySemantic proximity Read ↗

Functional Genetic Variation in the Anti-Müllerian Hormone Pathway in Women With Polycystic Ovary SyndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.