Article
Genetic alterations within the DENND1A gene in patients with polycystic ovary syndrome (PCOS).
PloS one - 1 Jan 2013
Eriksen Mette B, Nielsen Michael F B, Brusgaard Klaus, Tan Qihua, Andersen Marianne S, Glintborg Dorte, Gaster Michael
Abstract excerpt
Polycystic ovary syndrome (PCOS), the most common endocrine disease among premenopausal women, is caused by both genes and environment. We and others previously reported association between single nucleotide polymorphisms (SNPs) in the DENND1A gene and PCOS. We therefore sequenced the DENND1A gene in white patients with PCOS to identify possible alterations that may be implicated in the PCOS pathogenesis....
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