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Article

Role of gyrB Mutations in Pre-extensively and Extensively Drug-Resistant Tuberculosis in Thai Clinical Isolates.

Antimicrobial agents and chemotherapy - 1 Sept 2016

Disratthakit Areeya, Prammananan Therdsak, Tribuddharat Chanwit, Thaipisuttikul Iyarit, Doi Norio, Leechawengwongs Manoon, Chaiprasert Angkana

Abstract excerpt

DNA gyrase mutations are a major cause of quinolone resistance in Mycobacterium tuberculosis We therefore conducted the first comprehensive study to determine the diversity of gyrase mutations in pre-extensively drug-resistant (pre-XDR) (n = 71) and extensively drug-resistant (XDR) (n = 30) Thai clinical tuberculosis (TB) isolates. All pre-XDR-TB and XDR-TB isolates carried at least one mutation within the...

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Identifiers

PMID: 27297489
DOI: 10.1128/AAC.00539-16
PMCID: PMC4997844

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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